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    Lyme Disease & Co-infections

    Lyme disease is caused by the bacterium Borrelia burgdorferi and is transmitted through the bite of infected ticks. When not treated early or adequately, it can become chronic or late-stage, causing severe multi-systemic issues. Ticks often transmit other pathogens simultaneously, known as co-infections (e.g., Babesia, Bartonella).

    Common Symptoms

    Severe fatigue and malaise
    Migratory joint pain and swelling
    Neurological issues (neuropathy, brain fog, facial palsy)
    Heart palpitations (Lyme carditis)
    Fever, chills, and sweats (often associated with Babesia)

    Causes & Triggers

    • Tick bites carrying Borrelia and/or co-infections
    • Immune suppression allowing dormant infections to reactivate
    • Biofilm formation protecting bacteria from antibiotics

    Diagnosis

    Standard two-tier testing (ELISA and Western Blot) often misses late-stage or chronic cases. Functional medicine practitioners often rely on clinical diagnosis supported by specialized testing from labs like IGeneX, which test for multiple strains and co-infections.

    Treatment Approaches

    Extended or pulsed antibiotic therapy
    Herbal antimicrobials (e.g., Buhner protocol, Cowden protocol)
    Biofilm disruptors
    Detoxification support
    Immune modulation

    Not Sure Where to Start?

    Take our free Root Cause Assessment to help identify whether your symptoms are primarily driven by genetics, environmental toxins, or nervous system dysregulation.

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    Top Lyme Specialists

    View All
    Dr. Tania Dempsey, MD

    Dr. Tania Dempsey, MD

    Integrative Medicine, MCAS

    Purchase, NY
    Dr. Jill Carnahan, MD

    Dr. Jill Carnahan, MD

    Functional Medicine, Mold

    Louisville, CO
    Dr. Jess Peatross, MD

    Dr. Jess Peatross, MD

    Functional Medicine, Stealth Infections

    Virtual
    Telehealth
    Dr. Michael Ruscio, DC

    Dr. Michael Ruscio, DC

    Functional Medicine, Gut Health

    Austin, TX
    Telehealth
    View All Lyme Specialists

    Research & Sources

    Chronic Lyme disease: an evidence-based definition by the ILADS Working Group

    Expert Review of Anti-infective TherapyView Source

    Severity of chronic Lyme disease compared to other chronic conditions: a quality of life survey